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Functional PAMs of WZ_Cpf1 tested with PAM library in vitro and in vivo

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NIAID Data Ecosystem2026-05-26 收录
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We found a novel Cpf1 family member (here referred as WZ_Cpf1) with comparable genome editing activity to that of As-, Lb- and FnCpf1s. To further characterize its PAM preference, we utilized two reporter systems including PAM-DOSE system and in-vitro protein-based assay. Here shows the dataset from NGS.

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2019-04-23
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