ARL1:GTP binds ARFIP2
收藏reactome.org2025-01-15 收录
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Two hybrid screening with human ARL1 as bait identified ARFIP2 as a novel ARL1:GTP-interacting partner (Van Valkenburgh et al, 2001). Interaction between ARFIP2 and ARL1 increases the amount of ARL1:GTP four-fold , although the significance of this is not clear (Van Vlakenburgh et al, 2001). ARFIP2 is also known to interact with RAC1 and to influence membrane ruffling (van Aelst et al, 1996; Tarricone et al, 2001)
利用以人类ARL1作为诱饵的混合筛选实验,van Valkenburgh等人(2001年)鉴定出ARFIP2为一种新型的ARL1:GTP相互作用伙伴。ARFIP2与ARL1的相互作用使ARL1:GTP的数量增加四倍,尽管其意义尚不明确(van Vlakenburgh等人,2001年)。此外,ARFIP2还已知能与RAC1相互作用,并影响细胞膜皱褶(van Aelst等人,1996年;Tarricone等人,2001年)。
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