Phosphorylation stoichiometry reveal site-specific regulation on protein-protein interaction and signaling pathway
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https://www.omicsdi.org/dataset/jpost/PXD022658
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资源简介：
An ultrasensitive quantitative phosphoproteomic approach to measure the dynamic phosphorylation stoichiometry in oncoreceptor, its interaction proteins and downstream cellular proteins. Using epidermal growth factor receptor (EGFR) as a model, the γ-[18O4]-ATP kinase strategy greatly enhanced sensitivity to obtain 16 pY sites on EGFR in a single experiment and 4%-34% higher pathway mapping coverage.
创建时间：
2021-02-10
