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Summary Statistics from Genome-Wide Association Study on Chronic Thromboembolic Pulmonary Hypertension

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Figshare2025-12-18 更新2026-04-08 收录
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Final summary statistics from a GWAS on Chronic Thromboembolic Pulmonary Hypertension on patients of European ethnicity (1907 cases, 10363 controls). <br>Fields:CHR: chromosoneBP: base-pair coordinates (GRCh37)A1: reference alleleAF: reference allele frequencyP_META: final p-value from meta-analysisZ_META: associated z-score from meta-analysis with effect directionP_DISC: final p-value from discovery analysisP_REP: final p-value from replication analysisOR_IL: odds ratio from analysis of samples genotyped on Illumina arrays in discovery cohortOR_AF: odds ratio from analysis of samples genotyped on Affymetrix arrays in discovery cohortOR_REP: odds ratio from analysis of samples in replication cohort. <br>Submitted by author JL on behalf of all authors. Please see associated manuscript below for details.Liley J, Newnham M, Bleda M, Bunclark K, Auger W, Barbera JA, Bogaard H, Delcroix M, Fernandes TM, Howard L, Jenkins D. Shared and distinct genomics of chronic thromboembolic pulmonary hypertension and pulmonary embolism. American Journal of Respiratory and Critical Care Medicine. 2024 Jun 15;209(12):1477-85.
提供机构:
Lang, Irene; Graf, Stefan; Newnham, Michael; Simpson, Michael; Toshner, Mark; Pepke-Zaba, Joanna; Bleda, Marta; Auger, William; Morrell, Nicholas; Howard, Luke; Fernandes, Tim; Barbera, Joan Albert; Southgate, Laura; Wharton, John; Wilkins, Martin; Delcroix, Marion; Jenkins, David; Bogaard, Harm Jan; Bunclark, Katherine; Rhodes, Chris; Liley, James; Mayer, Eckhard; Trembath, Richard
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2025-12-18
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