Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity

Protein Data Bank Japan2023-12-13 更新2026-03-21 收录

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Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity Descriptor: 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION Authors: Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. Deposit date: 2005-05-04 Release date: 2005-05-12 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005

新型Chk1抑制剂的基于结构设计：氢键与蛋白-配体亲和力解析描述符：2-[(5,6-二苯基呋喃并[2,3-d]嘧啶-4-基)氨基]乙醇、丝氨酸/苏氨酸蛋白激酶CHK1、硫酸根离子作者：Foloppe, N.、Fisher, L.M.、Howes, R.、Kierstan, P.、Potter, A.、Robertson, A.G.S.、Surgenor, A.E. 入库日期：2005-05-04 发布日期：2005-05-12 最后修改日期：2023-12-13 实验方法：X射线衍射（2.1埃）引用文献：《新型Chk1抑制剂的基于结构设计：氢键与蛋白-配体亲和力解析》，J. Med. Chem., 2005年，第48卷

创建时间：

2005-05-04