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PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5c7s
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PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD) Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION Authors: Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) Deposit date: 2015-06-24 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Binding and mimicking of the phosphate-rich substrate, PRPP To Be Published

PRPP于结核分枝杆菌(Mycobacterium tuberculosis)邻氨基苯甲酸磷酸核糖转移酶(anthranilate phosphoribosyltransferase,AnPRT; trpD)的活性位点内与两个Mn²+结合。描述符:1-O-焦膦酰基-5-O-膦酰基-α-D-呋喃核糖(1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose)、邻氨基苯甲酸磷酸核糖转移酶、锰(II)离子(MANGANESE (II) ION)。作者:Evans G.L.、Baker E.N.、Lott J.S. 以及结核分枝杆菌结构基因组学联盟(TB Structural Genomics Consortium, TBSGC)。存档日期:2015年6月24日,发布日期:2016年6月29日,最后修改日期:2023年9月27日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.1 Å。引用:《富含磷酸酯的底物PRPP的结合与模拟》(待发表)
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2015-06-24
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