Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-3-ylmethoxy)phenyl)-4-methylquinolin-2-amine
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Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-3-ylmethoxy)phenyl)-4-methylquinolin-2-amine Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 7-{3-(aminomethyl)-4-[(pyridin-3-yl)methoxy]phenyl}-4-methylquinolin-2-amine, ... Authors: Chreifi, G, Li, H, Poulos, T.L. Deposit date: 2019-07-05 Release date: 2020-04-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. J.Med.Chem., 63, 2020
人内皮型一氧化氮合酶血红素结构域与7-(3-(氨基甲基)-4-(吡啶-3-基甲氧基)苯基)-4-甲基喹啉-2-胺复合物的晶体结构
配体描述：2-[双(2-羟乙基)氨基]-2-羟甲基丙烷-1,3-二醇、5,6,7,8-四氢生物蝶呤、7-{3-(氨基甲基)-4-[(吡啶-3-基)甲氧基]苯基}-4-甲基喹啉-2-胺等
作者：Chreifi, G、Li, H、Poulos, T.L.
提交日期：2019-07-05
发布日期：2020-04-29
最后修改日期：2023-10-11
实验方法：X射线衍射法（2.2 Å）
引用文献：First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. 《药物化学杂志》（J.Med.Chem.）, 63, 2020
创建时间：
2019-07-05
