Novel SLC-like proteins.

The table shows SLC-like human proteins from our search that are not in the classic group of SLCs (SLC1-52 families). The most similar (highest-scoring) TCDB family/subfamily and Pfam family are shown, as well as the most similar (highest-scoring) protein with structural information based on the pdb70 dataset (see Methods). Substrate information, where available, was retrieved from available literature. Based on our search, SLC families SLC53-66 have recently been incorporated into the nomenclature in collaboration with the HUGO/HGNC. Proteins marked with a single asterisk are included due to sequence similarity but may have functions other than transporter. Proteins marked with double asterisks might have a channel-like transport mechanism. For additional details, see S4 Table.