首页/数据集/The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells

The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells

NIAID Data Ecosystem2026-05-01 收录

RNA甲基化调控

肥大细胞功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE228615 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-09-07

RNA甲基化调控

反应机制

We observe the increase of stress resilience in Drosophila in which the m6A methyltransferase Mettl3 is knocked down. Mettl3-dependent m6A is present in the 5' UTR of genes enriched for neurogenesis a

NIAID Data Ecosystem110

Microarray analysis of Bone marrow derived mast cells (BMMCs) from C57BL/6 and ACKR2-/- mice. Microarray analysis of Bone marrow derived mast cells (BMMCs) from C57BL/6 and ACKR2-/- mice

肠道肿瘤免疫

肥大细胞功能

Mast cells have been suggested to either promote or suppress tumor progression but the mechanisms underlying these outcomes are unclear. Here, we show that mice with a heterozygous mutation in the ade

NIAID Data Ecosystem70

Source data for "PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation"

RNA甲基化调控

成骨细胞分化

The dataset included the source data of paper "PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation" published in communicat

Figshare2026-01-10 更新60

Increased Bone Mass in Female Mice Lacking Mast Cell Chymase

骨骼生物学

肥大细胞功能

Here we addressed the potential impact of chymase, a mast-cell restricted protease, on mouse bone phenotype. We show that female mice lacking the chymase Mcpt4 acquired a persistent expansion of diaph

NIAID Data Ecosystem100

Additional file 6 of Transcriptome-wide analysis of RNA m6A methylation regulation of muscle development in Queshan Black pigs

RNA甲基化调控

发育分子机制

Additional file 6: Table S6. All KEGG pathways for the DMGs.

Figshare2024-02-14 更新70