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Effect in MV4;11 cells of 3hr cortistatin A treatment on gene expression

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE65019
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资源简介:
We characterized the marine natural product cortistatin A (CA) as an inhibitor of CDK8 to determine whether pharmacologic inhibition of CDK8 regulates super-enhancer function and inhibits AML proliferation. In this series, we examine the transcriptional effect on MV4;11 cells of 3hrs exposure to CA to identify immediate effects. MV4;11 cells were treated in triplicate with either DMSO or CA for 3hrs. RNA was harvested and hybridized to microarrays to assess transcriptional changes.
创建时间:
2019-03-25
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