JenAge Ageing Factor Database

AgeFactDB is offline as of 2025-07-17 The JenAge Ageing Factor Database AgeFactDB is aimed at the collection and integration of ageing phenotype and lifespan data. Ageing factors are genes, chemical compounds or other factors such as dietary restriction, for example. In a first step ageing-related data are primarily taken from existing databases. In addition, new ageing-related information is included both by manual and automatic information extraction from the scientific literature. Based on a homology analysis, AgeFactDB also includes genes that are homologous to known ageing-related genes. These homologs are considered as candidate or putative ageing-related genes.JenAge老龄化因子数据库（AgeFactDB）致力于收集与整合老化表型和寿命数据。老化因子包括基因、化学化合物或其他因素，例如饮食限制等。在初步阶段，老化相关数据主要来源于现有数据库。此外，通过人工和自动信息提取科学文献中的新老化相关信息。基于同源性分析，AgeFactDB还纳入了与已知老化相关基因同源的基因。这些同源基因被视为潜在的或假定的老化相关基因。

搜集汇总

背景与挑战

背景概述

JenAge Ageing Factor Database是一个专注于衰老研究的数据库，收集和整合衰老表型与寿命数据，涵盖基因、化合物等多种衰老因素，并基于同源分析扩展候选基因。该数据库已于2025年7月17日离线，包含16,599个衰老因素和9,611个观察结果，由德国研究机构在2013年至2025年间维护。