Visuo-Cognitive Impairment in Multiple Sclerosis: Exploring the Relationship between Visual Processing and Cognitive Function in Early Disease

This thesis explores the relationship between visual and cognitive difficulties in the early stages of multiple sclerosis (MS), when these symptoms commonly appear. It shows that visual and cognitive symptoms can vary widely among MS patients and may not be initially noticed by clinicians during routine care. This research uses a novel framework that looks at how different parts of the visual system (e.g. sensory and motor symptoms) are related to cognition. Findings from this thesis suggest that visual symptoms are associated with poorer cognition and brain health, as well as increased disability. This work may help clinicians better understand early signs of disease progression in MS and highlights the value of using visual assessment to improve early detection of symptoms and guide treatment decisions.