Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)

Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) Descriptor: Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ... Authors: Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. Deposit date: 2023-10-18 Release date: 2024-05-01 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024T细胞受体（TCR）与结合KRAS-G12V肽（VVGAVGVGK）的人类白细胞抗原（HLA, Human Leukocyte Antigen）-A*11:01形成的复合物的晶体结构 描述项：β2-微球蛋白、KRAS-G12V九肽、主要组织相容性复合体（MHC, Major Histocompatibility Complex）I类抗原（片段），…… 作者：Zhang, M.Y、Luo, L.J、Xu, W、Guan, F.H、Wang, X.Y、Zhu, P、Zhang, J.H、Zhou, X.Y、Wang, F、Ye, S 入库日期：2023-10-18 发布日期：2024-05-01 最后修改日期：2024-10-09 实验方法：X射线衍射（分辨率2.17埃） 引用文献：靶向KRAS G12V肿瘤新抗原的T细胞受体的鉴定与亲和力增强. Commun Biol, 7, 2024