CRISPRi/a screen of doxorubicin induced cardiotoxicity
收藏NIAID Data Ecosystem2026-05-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP529937
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资源简介：
Druggable genome of CRISPRi/a sgRNA libraries for druggable genes protecting doxorubicin induced cardiomyocyte toxicity using human induced pluripotent stem cell (iPSC) derived cardiomyocytes. Overall design: Vehicle (DMSO) and doxorubicin treated iPSC differentiated cardiomyocytes (iCMs). iCMs were transfected with sgRNA libraries and CRISPRi (dCas9-KRAB) or CRISPRa (dCas9-VPR). Two biological replicates were used in both CRISPRi and CRISPRa screens.
创建时间：
2026-02-11
