Summary of the included studies evaluating risk factors and the association with acute endophthalmitis following cataract surgery.

Note: ED, electronic database; W, Internet search; CC, case-control; Coh, cohort; CS, cross-sectional; RO, retrospective observational; PO, prospective observational; PK, Penetrating keratoplasty; ECCE, extracapsular cataract extraction; ICCE, intracapsular extraction; AC IOL: anterior chamber intraocular lens; PC IOL: posterior chamber intraocular lens; NA, not available; NR, not recorded; N, domain not addressed. *Results were put into meta-analysis & OR/RR with 95% confidence interval is for all suspected endophthalmitis cases, not limited the confirmed (culture-positive) endophthalmitis. # GPC: Gram-positive cocci other than S. epidermidis. GNB: Gram-negative bacilli other than P. aeruginosa. GPB: Gram-positive bacilli other than P. Acnes. CNS*: Coagulase negative staphylococci; ?The quality criteria: A  =  consistent level 1 studies (1a-c), B  =  consistent level 2 or 3 studies or extrapolations from level 1 studies(2a–c,3a–b) 1a,SR (with homogeneity) of RCTs; 1b: Individual RCT (with narrow Confidence Interval);1c: all or none; 2a: SR (with homogeneity) of cohort studies;2b: Individual cohort study (including low quality RCT; e.g., <80% follow-up);2c: “Outcomes” Research; Ecological studies;3a: SR (with homogeneity*) of case-control studies;3b: Individual Case-Control Study. All the included studies have no conflict of Interest.