scRNA-seq analysis of infectious abdominal aortic aneurysms in human

Abdominal aortic aneurysm (AAA) and its more aggressive infectious variant (iAAA) are life-threatening conditions driven by chronic inflammation and aortic wall degradation, yet a comprehensive, high-resolution map of their cellular and molecular landscapes remains elusive. To address this, we performed integrated single-cell RNA sequencing of 190,214 cells from healthy, AAA, and iAAA human tissues, constructing a detailed cellular atlas of the abdominal aorta