Melanoma is a highly aggressive cancer with increasing incidence rates and a poor survival, particularly in patients with AJCC stage IV and advanced stage III. Deregulation of NF-kB is linked to diffe

NIAID Data Ecosystem70

Investigation of ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines. Investigation of ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines

黑色素瘤分子机制

RNA测序药物干预

We identified that upregulation of ST8SIA1 promotes melanoma brain metastasis. The goal of this RNA-seq is to analyze the ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines (DP-0

NIAID Data Ecosystem50

Additional file 9 of Suppression of Spry1 reduces HIF1α-dependent glycolysis and impairs angiogenesis in BRAF-mutant cutaneous melanoma

黑色素瘤分子机制

血管生成

Supplementary Material 9.

DataCite Commons2025-02-15 更新70

Importance of RAD6B in activation of canonical WNT signaling in melanoma development

黑色素瘤分子机制

Wnt信号通路调控

We have demonstrated that RAD6B, a ubiquitin conjugating enzyme that is a principal component of translesion synthesis pathway, stabilizes and transcriptionally activates beta-catenin by lysine 63-lin

NIAID Data Ecosystem60

Regulators of NRAS-mediated transformation and melanoma tumor maintenance

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