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Transcription profiling of pancreas from wild type and E2F1 knock-out mice to investigate insulin secretion control

Alliance of Genome Resources2026-08-01 收录

胰岛素分泌调节

E2F1基因敲除转录组

数据链接：

http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=E-MEXP-2243 数据链接链接失效反馈

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资源简介：

Total RNA was extracted from E2F1 +/+ and -/- pancreas and analysed by global gene expression

应用场景：

胰岛素分泌调节

TDP-43

TAR DNA-binding protein 43 kDa (TDP-43), encoded by TARDBP, is an RNA-binding protein, the nuclear depletion of which is the histopathological hallmark of amyotrophic lateral sclerosis (ALS). Here, we

NIAID Data Ecosystem70

Expression data from mouse insulinoma cells. Mus musculus

胰岛素分泌调节

细胞模型基因表达

We previously isolated a subclone, MIN6 clone 4, from the parental MIN6 cells, that shows well-regulated insulin secretion in response to glucose, glybenclamide, and KCl, even after prolonged culture.

NIAID Data Ecosystem20

Reduced basal insulin secretion from islets isolated from tafazzin deficient mice is associated with reduced mitochondrial function

胰岛β细胞线粒体功能障碍

胰岛素分泌调节

Tafazzin is a transacylase which causes the content and molecular structure of cardiolipin (CL) to be altered in the inner mitochondrial membrane. The enzymatic machinery responsible for oxidative res

NIAID Data Ecosystem10

AJP_Supplementary_data

胰岛素分泌调节

脂代谢与糖尿病

Sphingosine-1-phosphate as a key player of insulin secretion induced by high density lipoprotein treatment_supplementary_data

Figshare2019-12-04 更新30

Additional file 5: of Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells

胰岛素分泌调节

磷酸化信号通路

Table S3. Significantly regulated p-sites upon 60 min of glucose stimulation. The table shows p-site quantification of five experimental replicates performed on both experimental conditions (2.5 and 1

Figshare2019-02-21 更新20

Transcription profiling of pancreas from wild type and E2F1 knock-out mice to investigate insulin secretion control

资源简介：

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