Early-life thermal stress mediates long-term alterations in hypothalamic microglia [RNA-Seq]

We identified the microglial population in the chick anterior hypothalamus (AH) and showed that early-life thermal stress (on day 3 post-hatch) influences the inflammatory process in the AH, altering microglial transcriptomic signature in response to LPS treatment (on day 10 post-hatch). Microglial mRNA profile of 11-day-old non-conditioned/heat-conditioned saline-injected and non-conditioned/heat-conditioned LPS-injected chicks 24 h after the injection by 3'-mRNA- sequencing (RNA-seq)