ETV6::JAK2 T-ALL copy number alterations

NIAID Data Ecosystem2026-03-13 收录

白血病基因变异

拷贝数变异

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA844038 数据链接链接失效反馈

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资源简介：

Detection of copy number alterations in ETV6::JAK2;Rag2-/- and ETV6::JAK2;Rag2-/-;Cdkn2a+/- T-ALL by low-coverage WGS

创建时间：

2022-05-31

Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses

癌症基因组数据

拷贝数变异

Cell cultures were isolated from primary pancreatic cancers (PPTs) of KPC mice and subjected to array comparative genomic habridization (aCGH) for the investigation of copy nummber profiles. We genera

NIAID Data Ecosystem80

Somatic CNV profile of congenital ectopic thyroids

甲状腺功能异常

拷贝数变异

To assess whether specific genes have relevant somatic genetic or epigenetic alterations in ectopic tissue, we used a combined analysis of transcriptome (confirmed by qRT-PCR on 68 genes), methylome,

NIAID Data Ecosystem60

Molecular characterization of t(2;14)(q22;q32) and t(6;14)(q25;q32) translocations in mixed myeloid/T lymphoid leukemia patients.

白血病基因变异

基因融合与突变分析

We characterized two recurrent translocations, i.e. t(2;14)(q22.3;q32) and t(6;14)(q25;q32), in FLT3 positive mixed myeloid/T-cell lymphoid leukemias (MLPA). Both translocations involved BCL11B at 14q

NIAID Data Ecosystem50

HapMap Yoruban individuals vs CEPH reference

拷贝数变异

遗传多态性

It is becoming clear that copy number polymorphism in the human genome is a significant form of genetic variation. We have developed a new method that uses SNP genotype data from parent-offspring trio

NIAID Data Ecosystem70

Tumor Liver vs Normal Liver: ChIP-chip and RNA expression. Homo sapiens

肝癌转录组差异分析

拷贝数变异

There is widespread interest in efficient characterization of differences between tumor and normal samples. Here, we demonstrate an effective methodology for genome-scale characterization of tumors. U

NIAID Data Ecosystem50

ETV6::JAK2 T-ALL copy number alterations

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