Smart Triage: Clinical Data - PRST

This data is the Saving young lives: Triage and treatment using the pediatric rapid sepsis trigger (PRST) tool study. Data collected for this study occurred from April 2020 to April 2022. Objective(s): This is a pre-post intervention study involving pediatric patients presenting to the study hospitals in seek of medical care for an acute illness. The purpose of this study was to develop a prediction model and to perform clinical validation of a digital triage tool to guide triage and treatment of children at health facilities in LMICs with severe infections/suspected sepsis. The study involved three phases: (I) Baseline Period, (II) Interphase Period, (III) Intervention Period. The study hospitals include 2 sites in Kenya (1 control site, 1 experimental site) and 2 in Uganda (1 control site, 1 experimental site). Data Description: Predictor variables were collected at the time of triage by trained study nurses using a custom-built mobile application. All data entered into the mobile application was stored an encrypted database. Data was uploaded directly from the mobile device to a Research Electronic Data Capture (REDCap) database hosted at the BC Children’s Hospital Research Institute (Vancouver, Canada). Outcomes were obtained from facility records or telephone follow-up at 7-10 days and the data was collected electronically. Time-specific outcomes were tracked using an RFID tagging system with study personnel as backup. Limitations: There is missing data and some variables were not collected at all sites. Ethics Declaration: This study was approved by the Makerere University Higher Degrees research and Ethics Committee (No. 743), the Uganda National Institute of Science and Technology (HS 528ES), and the University of British Columbia / Children & Women’s Health Centre of British Columbia Research Ethics Board (H19-02398 & H20-00484). NOTE for restricted files: If you are not yet a CoLab member, please complete our membership application survey to gain access to restricted files within 2 business days. Some files may remain restricted to CoLab members. These files are deemed more sensitive by the file owner and are meant to be shared on a case-by-case basis. Please contact the CoLab coordinator at [e-mail] or visit our website.本数据集源自《拯救幼小生命：基于儿童快速脓毒症触发（pediatric rapid sepsis trigger, PRST）工具的分诊与治疗》研究。本研究的数据采集时间为2020年4月至2022年4月。 【研究目标】本研究为一项前后干预类研究，研究对象为因急性疾病前往合作医院就诊的儿科患者。本研究旨在开发一款预测模型，并对一款数字分诊工具开展临床验证，以指导低收入和中等收入国家（Low- and Middle-Income Countries, LMICs）医疗卫生机构中罹患重症感染/疑似脓毒症儿童的分诊与诊疗工作。本研究分为三个阶段：（I）基线期、（II）过渡阶段、（III）干预期。本次研究的合作医院共有4家，其中肯尼亚设2家（对照站点与试验站点各1家），乌干达设2家（对照站点与试验站点各1家）。 【数据说明】经培训的研究护士通过定制化移动应用程序，在分诊阶段收集预测变量数据。所有录入移动应用程序的数据均存储于加密数据库中。数据直接从移动设备上传至托管于加拿大温哥华不列颠哥伦比亚大学儿童医院研究所的研究电子数据采集（Research Electronic Data Capture, REDCap）数据库。结局数据通过医疗机构记录或7-10天后的电话随访获取，并以电子化方式采集。针对时间特异性结局指标，本研究采用射频识别（Radio Frequency Identification, RFID）标记系统进行追踪，并以研究人员作为备份保障。 【研究局限性】本研究存在数据缺失问题，且部分变量未在所有研究站点完成采集。 【伦理声明】本研究已获得马克雷雷大学高等教育研究与伦理委员会（批准号：743）、乌干达国家科学技术研究所（批准号：HS 528ES）以及不列颠哥伦比亚大学/不列颠哥伦比亚大学儿童与妇女健康中心研究伦理委员会（批准号：H19-02398与H20-00484）的批准。 【受限文件说明】若您尚未成为脓毒症协作实验室（CoLab）成员，请于2个工作日内完成成员申请调查以获取受限文件访问权限。部分文件仅对CoLab成员开放。文件所有者认为此类文件敏感性较高，将采取逐案审批的方式共享。请联系CoLab协调员，邮箱：[e-mail]，或访问官方网站。