TP53 binds the PTEN promoter
收藏reactome.org2025-01-21 收录
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PTEN (phosphatase and tensin homolog deleted in chromosome 10) is a tumor suppressor gene that is deleted or mutated in a variety of human cancers. TP53 (p53) binds to the p53-binding site at the PTEN promoter level (Stambolic et al. 2001).
PTEN(第10号染色体上缺失的磷酸酶和张力蛋白同源基因)是一种肿瘤抑制基因,在多种人类癌症中发生缺失或突变。TP53(p53)与PTEN启动子区域的p53结合位点相结合(Stambolic等,2001年)。
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