Kinetics of lucanthone and hycanthone binding to APE1.
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Hycanthone shows higher binding affinity as compared to Lucanthone. Data in Table 1 show affinity analysis of lucanthone (LUC) and hycanthone (HYC) binding to APE1 immobilized on CM5 chip (Figure 6A and 6B) using BIAsimulation software available at the Biacore facility at SUNYSB.RU = Resonance units are measure of changes in refractive index; ka = association constant; kd = dissociation constant and KD = Affinity constant. These data are representation of two independent repeats.
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2015-12-02



