Additional file 2: of Mechanistic interpretation of non-coding variants for discovering transcriptional regulators of drug response

The file includes seven supplementary tables. All supplementary tables are included as sheets in this Excel file. Legends for these tables are provided here. (1) Table S1. The number of motifs for each TF. (2) Table S2. Accuracy values (correlation coefficient) of binding strength predictions for each TF. (3) Table S3. The AUROCs and AUPRCs of TFs in the ASB enrichment using four different TF binding predictors. (4) Table S4. TFs discovered regulating drug response using Delta-MOP alone to predict binding-change SNPs. (5) Table S5. TFs discovered regulating drug response using Delta-gkm-SVM alone to predict binding-change SNPs. (6) Table S6. The results of drug associated enrichment tests for all 888 TF-drug pairs. (7) Table S7. Mediator genes in ELF1-doxorubicin Analysis. SNPs in the intersection of TF-drug hypergeometric tests are: (1) eQTLs associated to drug response genes; (2) â binding-change SNPsâ of the TF. DRGs associated with those SNPs are potentially mediators regulated by the TF. Here we list all mediator genes in ELF1-Docorubicin analysis. (XLS 149 kb)