Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment
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Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment Descriptor: ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, CHLORIDE ION, ... Authors: McIntyre, P.J, Collins, P.M, Vrzal, L, Birchall, K, Arnold, L.H, Mpamhanga, C, Coombs, P.J, Burgess, S.G, Richards, M.W, Winter, A, Veverka, V, von Delft, F, Merritt, A, Bayliss, R. Deposit date: 2017-08-16 Release date: 2017-11-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chem. Biol., 12, 2017
变构结合片段复合物中的极光激酶A（Aurora-A kinase）晶体结构
描述符：腺苷5'-二磷酸（ADENOSINE-5'-DIPHOSPHATE）、极光激酶A（Aurora kinase A）、氯离子（CHLORIDE ION）……
作者：McIntyre, P.J、Collins, P.M、Vrzal, L、Birchall, K、Arnold, L.H、Mpamhanga, C、Coombs, P.J、Burgess, S.G、Richards, M.W、Winter, A、Veverka, V、von Delft, F、Merritt, A、Bayliss, R
入库日期：2017-08-16
发布日期：2017-11-01
最后修改日期：2024-11-06
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.69埃
引用文献：采用生化、生物物理及基于片段的方法表征极光激酶A/TPX2相互作用中的三个可成药热点位点. ACS Chem. Biol., 12, 2017
创建时间：
2017-08-16
