Mesenchymal stromal cell transcriptome study. Homo sapiens

Transcriptomes of mesenchymal stromal cells from bone marrow (bmMSC) were compared to MSC from term placenta (pMSC). Cells were expanded under GMP-compliant conditions. The transcriptome was explored to compare the regenerative potential of bmMSCs and pMSCs in a pre-clinical and eventually in a clinical context Overall design: 25 samples, 11 bone marrow (no replicates) from male and female donors, 14 healthy human term placentas from planned cesareans. The study was approved by the Ethics Committee