Inhibition of IGF1R/IR and autophagy as an intervention in PDAC
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163348
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To determine whether suppression of IGF-1 signaling in was synergistic with inhibition of autophagy in PDAC, and to identify transcriptional response illicited mice were injeced with KPC MT4 cells s.c. and treated with vector BMS754807 or hydroxychloroquine alone or incombination. RNA was isolated from median tumors from each group and transcriptomics conducted 4 groups (n=6/group), Control, BMS754807 only, hydroxychloroquine only, BMS754807+hydroxychloroquine
创建时间：
2021-12-15
