Genome-wide maps of chromatin state in human primary CAR-T cells [ChIPseq, ATAC-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP319410
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资源简介：
We report the transcriptomic and epigentic profile of human primary CD19-28z CAR-T cells. Overall design: CRISPR gene editing was used to delete MED12 or the "safe harbor" control gene AAVS1. Gene-edited CAR-T cells were cultured in vitro for 15 days. Unstimulated cells were collected on day 15. Stimulated cells were collected after 3 hours of stimulation with plate-bound anti-idiotype antibodies specific for the CAR.
创建时间：
2022-12-10
