Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613

Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613 Descriptor: (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ... Authors: Zhao, Y, Zhang, Z. Deposit date: 2022-05-09 Release date: 2022-06-22 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of ligand binding modes of human EAAT2. Nat Commun, 13, 2022与人兴奋性氨基酸转运蛋白2（excitatory amino acid transporter 2, EAAT2）结合WAY-213613的复合物结构。配体描述：(2S)-2-氨基-4-[[4-[2-溴-4,5-二氟苯氧基]苯基]氨基]-4-氧代丁酸、1,2-二酰基-sn-甘油-3-磷酸胆碱、胆固醇半琥珀酸酯等。作者：Zhao, Y、Zhang, Z。存档日期：2022-05-09，发布日期：2022-06-22，最后修改日期：2025-07-02。实验方法：电子显微镜（分辨率3.4 Å）。引用文献：《人EAAT2配体结合模式的结构基础》，《自然-通讯》，2022年，第13卷。