comparison of MILI+/- and MILI-/- at D10 testis. Mus musculus

Spermatogenesis in MILI-KO mice was blocked completely at early prophase of the first meiosis during the zygotene and early pachytene stage. To analyze the molecular basis of MILI function, we examined the difference between gene expression for MILI-/- and MILI+/- testes. Keywords: total RNAs of day10 testes Overall design: To exclude secondary effects, we prepared mRNA from day10 mice. Because the apoptotic cells in KO testis were observed at day11 after birth.