All viruses that naturally jumped the species barrier had some capacity to antagonize the new species APOBEC3G.

a, Virus from which the vif gene was taken. Vif proteins are from viruses that crossed to a new host species.b, Host species from which APOBEC3G was taken. APOBEC3G proteins are from recipient host species.c, Infectivity of viral constructs produced in the presence of APOBEC3G (relative to no APOBEC3G).d, Virus that resulted from the cross-species transmission event(s).e, References: Etienne et al. 2013 [4], Compton et al. 2013 [20], Letko et al 2013 [56], D’Arc et al. 2015 [11], others are data from this study (Figs 1B and S2).Sensitivity of APOBEC3G (from the recipient host species) to the SIV Vif protein (from the virus that crossed the species barrier); infectivity of viruses produced in the presence of APOBEC3G is reported as a percentage, relative to infectivity in the absence of APOBEC3G (100%).