Composition of microbiota for dominant and sub dominant bacteria groups in healthy and advanced colorectal neoplasia patients.

N: represents the numbers of patients; *Advanced neoplasia: advanced neoplasia included advanced adenomas (adenomas measuring >10 mm or adenomas with high-grade dysplasia, or in situ carcinoma) and invasive CRC (invasion of malignant cells beyond the muscularis mucosae); †Comparison of continuous variables was performed using Student T-test or Wilcoxontest whenever appropriate; ⊥All-bacteria results obtained by qPCR were expressed as mean of the log10 value ± SD, ‡Results were expressed as mean of normalized values ± SD, calculated as the log number of targeted bacteria minus the log number of all-bacteria. Faecalibacterium prausnitzii is the major component of Clostridium leptum group.