Visible-Light-Induced Photocatalytic Trifluoromethylation of Bunte Salts: Easy Access to Trifluoromethylthiolated Synthons

A metal-free visible-light-induced trifluoromethylation
of Bunte
salts of α-bromoketones/alkyl bromide/benzyl bromides/functionalized
allyl (Baylis–Hillman) bromides has been accomplished using
Langlois’ reagent in the presence of inexpensive eosin Y as
a photocatalyst to form the privileged trifluoromethylthiolated synthons.
The method is straightforward, operationally simple, and endowed with
broad substrate scope and good functional group tolerance.