Aguilar-Pineda et al. Structural and functional analysis of female sex hormones against SARS-Cov-2 cell entry

This dataset contains all the raw data and codes used for th adquision of the data presented in the manuscript: "Structural and functional analysis of female sex hormones against SARS-Cov-2 cell entry " by Aguilar-Pineda et al. Here we report new insights into the molecular basis of the interactions between the SARS-CoV-2 spike (S) protein and the human ACE2 receptor. We further report that glycosylation of the ACE2 receptor enhances SARS-CoV-2 infectivity. Importantly estrogens can disrupt glycan-glycan interactions and glycan-protein interactions between the human ACE2 and the SARS-CoV2 thereby blocking its entry into cells.