Regional and laminar distribution of receptors for GABA in the rat brain (v2)
收藏DataCite Commons2024-03-02 更新2024-07-13 收录
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资源简介:
The present dataset provides the quantitative regional and laminar distribution of key molecules of inhibitory neurotransmission, namely the γ-aminobutyric acid (GABA) receptors GABA<sub>A</sub> and GABA<sub>B</sub> as well as the peripheral benzodiazepine (perBZ) receptors and the GABA<sub>A</sub> associated benzodiazepine (GABA<sub>A</sub>/BZ) binding sites, in five selected rostrocaudal levels of the rat brain. The receptors were visualized by means of quantitative *in vitro* receptor autoradiography and the selective tritiated ligands muscimol, CGP 54626 and flumazenil. The high spatial resolution of this method enables quantification of receptor densities in anatomically identifiable cortical structures as detailed as the hippocampal regions and layers, or subcortical structures such as amygdalar nuclei. We also provide information about image data registration to the Waxholm Sprague Dawley rat brain atlas.
提供机构:
EBRAINS
创建时间:
2024-03-02



