INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1310876699

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1310876699 Descriptor: 2-fluoro-N-[2-(pyridin-4-yl)ethyl]benzamide, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA分析小组提交数据集——SHIP1的磷酸酶结构域与C2结构域（C2 domain）结合Z1310876699的复合物晶体结构，配体标识：2-氟-N-[2-(吡啶-4-基)乙基]苯甲酰胺、二甲基亚砜（DIMETHYL SULFOXIDE）、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1（Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1）。作者：Bradshaw W.J.、Newman J.A.、von Delft F.、Arrowsmith C.H.、Edwards A.M.、Bountra C.、Gileadi O.。提交日期：2020-10-30；发布日期：2020-11-11；最后修改日期：2026-02-18。实验方法：X射线衍射（分辨率1.38埃）。引用文献：《通过SHIP1与SHIP2的C2结构域调控肌醇5-磷酸酶活性》，《Structure》，2024年。