CDK2/Cyclin A in complex with compound 73
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CDK2/Cyclin A in complex with compound 73 Descriptor: 4-[[6-(3-phenylphenyl)-7~{H}-purin-2-yl]amino]benzenesulfonamide, Cyclin-A2, Cyclin-dependent kinase 2 Authors: Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E.M, Newell, D.R, Turner, D, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Cano, G. Deposit date: 2017-03-12 Release date: 2017-03-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J. Med. Chem., 60, 2017
CDK2/细胞周期蛋白A（Cyclin A）与化合物73的复合物 描述项：4-[[6-(3-联苯基)-7H-嘌呤-2-基]氨基]苯磺酰胺、细胞周期蛋白A2（Cyclin-A2）、细胞周期蛋白依赖性激酶2（Cyclin-dependent kinase 2）
作者：Coxon, C.R、Anscombe, E、Harnor, S.J、Martin, M.P、Carbain, B、Hardcastle, I.R、Harlow, L.K、Korolchuk, S、Matheson, C.J、Noble, M.E.M、Newell, D.R、Turner, D、Sivaprakasam, M、Wang, L.Z、Wong, C、Golding, B.T、Griffin, R.J、Cano, G.
提交日期：2017-03-12
发布日期：2017-03-29
最后修改日期：2024-10-16
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.97埃（Å）
引用文献：Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J. Med. Chem., 60, 2017，即《细胞周期蛋白依赖性激酶（CDK）抑制剂：6-取代2-芳基氨基嘌呤类化合物的构效关系及CDK2选择性研究》，刊载于《J. Med. Chem.》2017年第60卷
创建时间：
2017-03-12
