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Photoregulation of G-quadruplex DNA by non-covalent azobenzene photoswitches

B2FIND2026-05-30 收录

G-四链体调控

光开关核酸工程

数据链接：

https://b2find.eudat.eu/dataset/389f10f0-304f-566b-8a92-e8f92349d367 数据链接链接失效反馈

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资源简介：

G-quadruplexes (G4s) are transient DNA structures playing key role in cellular regulatory functions. Therefore, the reversible control of their formation/stabilisation using...

应用场景：

G-四链体调控

转录因子结合分析

Additional file 4: Table S3. Enrichment at G4 ChIP for TFs that have been mapped in both K562 and HepG2. The maximum enrichment was used if TFs have been mapped multiple times.

Figshare2021-04-24 更新70

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G‑Quadruplex-Binding Small Molecule

癌症靶向治疗

G-四链体调控

Human pancreatic ductal adenocarcinoma (PDAC) involves the dysregulation of multiple signaling pathways. A novel approach to the treatment of PDAC is described, involving the targeting of cancer genes

NIAID Data Ecosystem40

Bisquinolinium Compounds Induce Quadruplex-Specific Transcriptome Changes in HeLa S3 Cell Line

G-四链体调控

化合物诱导基因表达

Bisquinolinium Compounds Induce Quadruplex-Specific Transcriptome Changes in HeLa S3 Cell Line

ChEBI2012-05-29 更新20

Comparative genome-wide transcriptional profile after RTEL1 depletion and G4 stabilisation.

G-四链体调控

RNA测序基因表达分析

The goal of this study is to compare the transcription profile of mouse embryonic fibroblasts upon deletion of the helicase RTEL1 and stabilisation of G-quadruplexes (G4) with the G4 stabilisation dru

NIAID Data Ecosystem60

Additional file 8: of Relationships between putative G-quadruplex-forming sequences, RecQ helicases, and transcription

G-四链体调控

表观遗传建模

R code for mapping PQS to TSS for epigenetic modeling of gene expression method. Program written in R that identifies all PQS within 2 kbp of TSS, calculates relative distance between PQS and TSS, ide

NIAID Data Ecosystem20

Photoregulation of G-quadruplex DNA by non-covalent azobenzene photoswitches

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