Round or columnar and hypertrophic chondrocytes of Tric-b-KO mice

To survey altered gene expreesion in round, colmnar and hypertrophic chondrocytes of Tric-b-KO mice, total RNA preparations from round chondrocytes and colmnar/hypertrophic chondrocytes were subjected to gene microarray analysis. Results provide insight into the transcriptional profile of each Tric-b-KO chondrocyte and provide further insight into their functions. Total RNA preparations from three Tric-b-KO femoral cartilage plate portions enriched with round chondrocytes or columnar/hypertrophic chondrocytes were mixed and then subjected to Affymetrix Mus musculus microarrays. Round chondrocytes and columnar/hypertrophic chondrocytes were analyzed.