The Synthesis and Preliminary Biological Evaluation of a Novel Steroid with Neurotrophic Activity: NGA0187
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https://figshare.com/articles/dataset/The_Synthesis_and_Preliminary_Biological_Evaluation_of_a_Novel_Steroid_with_Neurotrophic_Activity_NGA0187/3255031
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资源简介：
A full account of the total synthesis of neurotrophic compound NGA0187 is provided. A key feature
of the synthesis involved the direct selective oxidation of 6α,7β-diol to install the unusual 6,7-ketol
moiety and stereoselective conjugate addition of vinyl cuprate to enone. A preliminary evaluation
of its ability to stimulate the neurite outgrowth was also evaluated with PC12 cell.
创建时间：
2005-11-25
