APH1B
收藏rgd.mcw.edu2025-01-21 收录
下载链接：
https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1344589
下载链接
链接失效反馈官方服务：
资源简介：
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
该基因编码一种多跨膜蛋白，该蛋白是γ-分泌酶复合体的功能性组分之一，该复合体还包含前蛋白和尼卡斯特林。该蛋白在复合体中作为前蛋白全蛋白的稳定辅因子。γ-分泌酶复合体催化整合蛋白如 notch 受体和β-淀粉样蛋白前体的裂解。[由 RefSeq 提供，2011 年 9 月]
提供机构：
Rat Genome Database
