Pfn1

ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding; signaling receptor binding; actin binding (ortholog); INVOLVED IN cellular response to growth factor stimulus; positive regulation of DNA metabolic process; positive regulation of stress fiber assembly; ASSOCIATED WITH membranoproliferative glomerulonephritis; amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 18 (ortholog); FOUND IN parallel fiber to Purkinje cell synapse; postsynapse; presynapse; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether

编码一种具有磷脂酰肌醇-4,5-二磷酸结合能力、信号受体结合能力、肌动蛋白结合能力（同源）的蛋白质；参与细胞对生长因子刺激的响应；正向调控DNA代谢过程；正向调控应力纤维组装；与膜增殖性肾小球肾炎相关；与肌萎缩侧索硬化症（同源）相关；与肌萎缩侧索硬化症第18型（同源）相关；存在于平行纤维与浦肯野细胞突触；突触后；突触前；与（S）-尼古丁、2,3,7,8-四氯二苯并二噁英、2,4-二溴苯基2,4,5-三溴苯基醚相互作用。