Unprecedented Palladium-Catalyzed Cross-Coupling Reaction of α-Bromo Sulfoxides with Boronic Acids

A new Suzuki-type palladium-catalyzed reaction of boronic acids with α-bromo sulfoxides has been developed using a protocol similar to the
well-documented reaction of boronic acids with aryl halides. Both cross-coupling and homocoupling processes were observed. The best
yields in cross-coupling products were obtained when the presence of oxygen was carefully excluded using degassed solvents. The oxidative
addition palladium complex intermediate could be isolated and characterized by X-ray single-crystal diffraction.