Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751)

Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751) Descriptor: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1, SULFATE ION Authors: Matsuura, Y. Deposit date: 2022-11-07 Release date: 2023-02-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha. Biochem.Biophys.Res.Commun., 652, 2023结合HIF-1α（HIF-1alpha）核定位信号（缺失724-751位）的输入蛋白α1（importin-alpha1）晶体结构。描述项：缺氧诱导因子1α（Hypoxia-inducible factor 1-alpha）、输入蛋白α1亚基（Importin subunit alpha-1）、硫酸根离子（SULFATE ION）。作者：Matsuura, Y.。提交日期：2022-11-07。发布日期：2023-02-22。最后修改日期：2023-11-29。解析方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.9埃（Å）。引用文献：结合HIF-1α（HIF-1alpha）二分核定位信号的野生型及内部缺失突变体的输入蛋白α复合物结构。Biochem.Biophys.Res.Commun., 652, 2023