Temperature-Dependent Rankings of Well-Established Hsp90 Interactors.

ORFs with three or more established interactions in BioGRID at the time of analysis are included in the table. If an ORF is essential or encodes a known Hsp90 cochaperone or folding client, that is indicated. The type(s) of Hsp90 interaction, physical (P) or genetic (G), is also specified for each ORF. For each screen and temperature condition, the numerical ranking of each ORF, out of all tested ORFs, with regard to sensitivity to Hsp90 inhibition is listed, with smaller numbers indicating a stronger growth defect. nd = not determined.