Biochemical reactions at kinetochore-microtubule interface.

Enzymatic reactions (e.g., phosphorylation and dephosphorylation) and association-dissociation reactions, which involve the MT associated protein Ndc80 linking MTs with KTs, and the reaction rate constants and characteristic timescales. The subscript p = 0, 1,…,6 denotes the number of phosphate groups attached to Ndc80 and changes in the rate constants and reaction propensities for MT-Ndc80 complex dissociation.