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Cyclic α,β-Tetrapeptoids: Sequence-Dependent Cyclization and Conformational Preference

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Cyclic_Tetrapeptoids_Sequence_Dependent_Cyclization_and_Conformational_Preference/2394874
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The presence of at least one N-Cα branched side chain is crucial for successful cyclization of α,β-tetrapeptoids. The ctct amide sequence revealed in the crystal structure of the 14-membered cyclotetrapeptoid 8 is also the most populated conformation in solution and is reminiscent of the predominant amide arrangement of the 12-membered cyclic tetrapeptides (CTPs).
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2016-02-19
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