Regression models: Association of high levels (80th percentile) of serum IgG to selected periodontal species and incident AD.

Model 1: bivariate association with single periodontal antibody.Model 2: controlled for age at phlebotomy (baseline).Model 3: Model 2, also controlled for APOE status, gender, and education.Model 4: Model 3, also controlled for hypertension, smoking, stroke, and diabetes.*Models shown using pseudolikelihood estimator, robust variance estimator, and weight of cases (1), controls (10) [most conservative method]; HR: Hazard ratio.Regression models: Association of high levels (80th percentile) of serum IgG to selected periodontal species and incident AD.