Microplitis bicoloratus bracovirus regulates critical signaling pathways during the innate immunosuppression and cell death of host Spodoptera litura hemocytes

ymbiotic polydnaviruses (PDVs) associated with parasitoids attack host immune system to protect parasitoid larvae development in host hemocoel. Microplitis bicoloratus bracovirus (MbBV) induces apoptosis of host Spodoptera litura hemocytes. Here, the transcription of hemocytes from non-parasitized and parasitized by M. bicoloratus contained over 11.63 G bp assembled sequence with 89,456 predicted genes and up-regulated genes 904 and down-regulated genes 5,572 during apoptosis. Study goals