The small intestine has a robust regenerative capacity, and various cell types serve as âcells-of-originâ in the epithelial regeneration process after injury. However, how much each population con
Background and Aims: Analysis of aging-induced impairments in satellite cells (SCs) â the stem cells of skeletal muscle that are required for its regeneration. Hox genes are known to control stem ce
Tissue homeostasis requires long-term lineage fidelity of somatic stem cells. Whether and how age-related changes in somatic stem cells impact the faithful execution of lineage decisions remains large
The N6-methyladenosine (m6A) has been shown to regulate stability and translation of messenger RNA (mRNA) in various biological processes. Here, we show that the knockout of the m6A writer Mettl3 or a
